Objective

To determine if women who were randomized to a mind/body program before starting their first IVF cycle would have higher pregnancy rates than control subjects.

Design

Randomized, controlled, prospective study.

Setting

Private academically affiliated infertility center.

Patient(s)

A total of 143 women aged ≤40 years who were about to begin their first IVF cycle.

Intervention(s)

Subjects were randomized to a ten-session mind/body program (MB) or a control group and followed for two IVF cycles.

Main Outcome Measure(s)

Clinical pregnancy rate.

Result(s)

Only 9% of the MB participants had attended at least one-half of their sessions at cycle 1 start. Pregnancy rates for cycle 1 were 43% for all subjects; 76% of the MB subjects had attended at least one-half of their sessions at cycle 2 start. Pregnancy rates for cycle 2 were 52% for MB and 20% for control.

Conclusion(s)

MB participation was associated with increased pregnancy rates for cycle 2, prior to which most subjects had attended at least half of their sessions.